Objective: To develop and validate a simple geriatric screening tool that performs as well as more complex assessments Background: Many tools that predict treatment risk in older adults are impractical for routine clinical use. Methods: We prospectively conducted comprehensive preoperative evaluations on 1025 patients age ≥75 years who presented to Sinai Hospital of Baltimore for major elective surgery, then retrospectively reviewed patients' medical records for occurrence of postoperative outcomes. Using logistic regression modeling and receiver operating characteristic curve analysis we selected the best combination of simple tests, labeling this the Sinai Abbreviated Geriatric Evaluation (SAGE). The performance of the SAGE was then compared with 3 standard tools in its power to predict postoperative outcomes. Results: The SAGE is a statistically significant predictor of postoperative outcomes. Each unit decrease in SAGE score was significantly associated with a 51% (95% CI 1.30–1.77) increase in odds of a complication, a 2-fold increase in odds of postoperative delirium (95% CI 1.65–2.66), a 27% increase in odds of length of hospital stay >2 days (95% CI 1.10–1.47), a 54% increase in odds of a hospital readmission within 30 days (95% CI 1.25–2.88), and a 38% increase in odds of an unanticipated discharge to higher-level care (95% CI 1.18–1.61). We estimated the receiver operating characteristic curve area under the curve (AUC) for the SAGE of 0.69, 0.77, 0.73, 0.66, and 0.78 for the above outcomes, respectively. The SAGE performed as well in predicting postoperative outcomes as Fried's frailty phenotype, Charlson Comorbidity Index, and American Society of Anesthesiologists Physical Status Class (ASA). Conclusion: The SAGE performs as well as other geriatric evaluations that require equipment or memorization.
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Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
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heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
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