Effects of Intravenous Cold Saline on Hyperthermic Athletes Representative of Large Football Players and Small Endurance Runners

Objective: To evaluate the cooling effects of intravenous (IV) cold normal (0.9%) saline on hyperthermic athletes. Design: Randomized crossover study design. Setting: Controlled research laboratory. Participants: Twelve male participants who were representative of a collegiate cross-country (6) and American football (6) population. Interventions: Participants underwent body composition analysis using a BodPod. They were placed in an environmentally controlled chamber and brought to a Tc of 39.5°C with dynamic exercise. When temperatures were reached, they were treated with either 2 L of cold saline (CS) (4°C) or intravenous room temperature (22°C) saline (RS) over a ∼30-minute period. Tre was measured with a rectal temperature probe every minute during the treatment period. Main Outcome Measures: Total ΔTre (ending Tre − starting Tre) and cooling rate (total change in Tre/time) were measured for each condition, and body composition variables calculated included body surface area (BSA), BSA-to-mass ratio (BSA/mass), lean body mass, and body fat percentage (%BF) (P

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