Woman With Headache and Amnesia

A 73-year-old woman presented with a severe headache, confusion, and primarily anterograde amnesia. She was febrile and had no focal neurologic deficits. Her lumbar puncture revealed elevated protein level, hypoglycorrhachia, and a lymphocytic pleocytosis. Magnetic resonance imaging (MRI) of the brain revealed a left-predominant region of hyperintensity on the fluid-attenuated inversion recovery sequence in the anterior medial temporal lobe (Figure 1) including the hippocampus and surrounding structures (Figure 2).

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