The effect of pelvic floor muscle contraction on detrusor overactivity pressure in neurogenic and non-neurogenic women during urodynamic study: a cross-sectional study

Objective The aim of this study was to investigate if detrusor overactivity (DO) can be influenced by a pelvic floor muscle (PFM) contraction in multiple sclerosis-associated overactive bladder (MS) and idiopathic overactive bladder (OAB) volunteers and compare urodynamic findings between the two groups. Design Eighteen women with MS and seventeen women with OAB responded the OAB-V8 questionnaire and performed urodynamic study (UDS) with electromyography of PFM to confirm the presence of a 15-seconds PFM contraction during a DO, when present. Variables were: OAB-V8 questionnaire, maximum cystometric capacity, volume at first DO, maximum DO amplitude and percentage of DO pressure reduction. Results All participants had a reduction in DO pressure when PFM contraction was requested. MS group showed significant higher DO amplitude than OAB group (p=0.02). OAB group had their DO pressure reduced in a greater extent when compared to MS group (p=0.01). Conclusion The results suggest that PFM contraction is able to reduce DO pressure in MS and OAB population. Corresponding author's contact information: Name: Adelia Lucio, Email address:adeliaclucio@gmail.com, Mailing address: R. Vital Brasil, 250 - Cidade Universitária Zeferino Vaz, Distrito de Barão Geraldo. Serviço de Urologia - Hospital das Clínicas Unicamp, 2°andar, A2 – sala 108. Campinas, SP, Brasil. Zip code: 13083-590. Telephone/Fax number: +55-19-3521-7481. Author Disclosures: Competing Interests: None a. Funding: Financial support was provided by FAPESP (Grant N° 2010/51656-5). b. Financial benefits to the authors: None c. Details of any previous presentation of the research, manuscript, or abstract in any form: None. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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