Reply

We thank the members of the European Advocacy Organization (EAO) for providing a parental perspective on pediatric acute-onset neuropsychiatric syndrome (PANS)/pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS). We wish to emphasize that we share a sincere concern for children diagnosed with these disorders or presenting with the sudden onset of neuropsychiatric symptoms. It is essential, however, that families and doctors be aware of existing controversies and that future well-designed scientific protocols address those.

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