Phase 1 study of spinal cord constraint relaxation with single session spine stereotactic radiosurgery in the primary management of patients with inoperable, previously unirradiated metastatic epidural spinal cord compression

In this Phase 1 prospective clinical trial, spinal cord dose constraint relaxation up to 16 Gy was not associated with any myelopathy events and may be considered in high risk inoperable patients with epidural disease, or metastatic epidural spinal cord compression to optimize local control.

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