P112. Modulatory effects of anodal transcranial direct current stimulation on fronto-striatal gain control of the interplay between selective attention and perception

Carrying conversations in public spaces with a plethora of competing sensory inputs demands flexible interactions between attention and perception for selectively processing goal-relevant information. We postulate that the fronto-striatal network plays a key role in regulating this interaction. However, to date the underlying gain control mechanisms are not yet well understood. Neuronal gain control can be fine-tuned by membrane potential regulated changes in neuronal excitability. Anodal transcranial current stimulation (atDCS) has been shown to cause a depolarization of resting membrane potentials, which increases neuronal excitability.

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