Imaging-Based Outcomes for 24 Gy in 2 Daily Fractions for Patients with De Novo Spinal Metastases treated with Spine Stereotactic Body Radiotherapy (SBRT)

This study reports mature outcomes for a large cohort of patients with no prior radiation (de novo) treated uniformly with 24 Gy in 2 daily spine SBRT fractions for metastases, which represents the SBRT regimen under evaluation on the ongoing SC-24 phase III randomized trial (NCT02512965). This fractionation is safe and effective in achieving high tumor control rates and the outcomes presented will serve as the benchmark data for SC-24.

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