Brain Metastasis of Medullary Thyroid Carcinoma Without Macroscopic Calcification Detected First on 68Ga-Dotatate and Then on 18F-Fluoride PET/CT

We report a case of a medullary thyroid carcinoma noncalcified brain metastasis characterized on 68Ga-dotatate PET/CT but not on an 18F-fluoride PET/CT performed 1 month later. Subsequent 18F-fluoride PET/CT studies performed 7 and 19 months after the 68Ga-dotatate PET/CT study demonstrated focal uptake in the metastasis. The CT images of the last PET/CT study also depicted a small focus of calcification beginning in the metastatic site.

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