Definitive Carbon-Ion Radiation Therapy for Locally Advanced Sinonasal Malignant Tumors: Subgroup Analysis of a Multicenter Study by the Japan Carbon-Ion Radiation Oncology Study Group (J-CROS)

We evaluated the safety and efficacy of definitive carbon-ion radiation therapy for sinonasal malignant tumors in a retrospective multicenter study. The study included 458 patients who had locally advanced tumors that were mainly radioresistant. Carbon-ion radiation therapy resulted in good local control and overall survival with acceptable toxicities.

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