Tracking the central and peripheral origin of tremor

Human motor control is a highly complex process that requires extraordinary precision to achieve optimal speed and accuracy of each movement. The dysfunction of the motor control system leads to a variety of movement disorders such as parkinsonism, dystonia, and ataxia. How the nervous system governs the movements in both physiological and pathological conditions in real time remains unclear, partly due to the rather complex nature of movements and the corresponding neurophysiology. Tremor is a type of movement with enriched information (phase, frequency, and amplitude) that can be tracked in real time to correlate with oscillatory neuronal activities in the brain, providing a very unique platform to study human motor control (McAuley and Marsden, 2000).

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