(OA04) Patterns of Failure After Postoperative Radiation Therapy for Locally Advanced NSCLC: Implications for Shifting Toward More Conformal Radiation Fields

Over the past decade, postoperative radiation therapy (PORT) volumes in locally advanced NSCLC have largely shifted from whole mediastinum to conformal fields as specified in the phase III Lung Adjuvant Radiotherapy Trial (Lung ART) trial. However, limited data is available on how this transition will affect locoregional recurrence rates (LRR) and overall survival (OS). We thus compared patterns of failure, survival outcomes, and toxicity with whole mediastinum (WM) radiation therapy vs. high-risk (HR) conformal fields in the postoperative setting.

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