Gastric Metastasis of Prostate Cancer as an Unusual Presentation Using 68Ga–Prostate-Specific Membrane Antigen PET/CT

A 79-year-old man with prostate cancer underwent 68Ga prostate-specific membrane antigen (68Ga-PSMA) dual-time-point PET/CT scan to evaluate tumor activity due to early satiety, unquantified weight loss, and elevation of prostate-specific antigen (PSA), demonstrating thickening of the gastric wall with intense tracer uptake. The immunohistochemistry of gastric biopsy showed CDX2 and CK20: negative; CK7, focal positive; PSA, positive, which confirmed metastatic disease. Metastatic disease was also found in bones, right lung, and retroperitoneal and pelvic lymphadenopathies.

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