Emerging MR Imaging Technologies for Radiation Therapy Planning and Response Assessment

Functional and molecular MRI techniques are capable of measuring biologic properties of tumor tissue. Knowledge of these biologic properties may improve radiation treatment by more accurately identifying tumor volumes, characterizing radioresistant subvolumes of tumor before radiation therapy (RT) and identifying recurrent disease following RT. Intravoxel incoherent motion (IVIM) MRI, blood oxygenation level dependent (BOLD) MRI, tissue oxygenation level dependent (TOLD) MRI, hyperpolarized 13C MRI, and chemical exchange saturation transfer (CEST) MRI are relatively new MRI techniques that have shown promise for contributing to RT planning and response assessment.

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