Daily Image-Guidance with Cone Beam Computed Tomography May Reduce Radiation Pneumonitis in Unresectable Non-Small Cell Lung Cancer

We found a decreased rate of Grade ≥ 2 radiation pneumonitis among inoperable non-small cell lung cancer patients receiving daily image-guided radiation therapy (IGRT) with cone-beam computed tomography (CBCT) after an initial 4-dimensional computed tomography simulation compared to daily IGRT with 2-dimensional orthogonal kilovoltage imaging. Future studies should consider the ability of CBCT to improve tumor localization and potentially reduce subacute pulmonary toxicity.

https://ift.tt/2Ijw1hb