Polypoid lesions from the oesophagus to colon

Clinical presentation

A 73-year-old man presented with abdominal fullness for 2 months. He had lost 5 kg in the previous 2 months. He did not have fever or abdominal pain. He had a history of chronic hepatitis B. Physical examination showed enlarged lymph nodes over bilateral neck, axillary and inguinal areas. Laboratory study revealed leucocytosis with white cell counts 14.1x10⁹/L; haemoglobin level 12.8 g/dL; platelet count 227x10⁹/L; hypoalbuminaemia with albumin level 2.8 g/dL, as well as normal blood sugar, aminotransferase, urea, creatine, serum uric acid and lactic acid dehydrogenase levels. Tumour markers carcinoembryonic antigen, carbohydrate antigen 19–9 and alpha-fetoprotein were all within normal limits. The upper GI panendoscopy showed multiple whitish sessile polypoid lesions over the whole circumference of oesophagus, extending form upper third to the gastro-oesophageal junction (figure 1A). Enlarged gastric rugae with polypoid lesions were seen from the fundus to the body of the stomach, and numerous erosive lesions...

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