The role of N6-methyladenosine (m6A) modification in normal and malignant hematopoiesis remains elusive. Weng et al. report the essential role of METTL14, a key component of the m6A methyltransferase complex, in self-renewal and differentiation of hematopoietic/leukemic stem cells and reveal the SPI1-METTL14-MYB/MYC signaling axis in myelopoiesis and leukemogenesis.
http://ift.tt/2llxUQs
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
▼
2017
(44259)
-
▼
Δεκεμβρίου
(5110)
-
▼
Δεκ 28
(223)
- Association between investigator-measured body-mas...
- Progressive delayed hemidystonia following clinica...
- Endobronchial metastasis of mixed Mullerian tumour...
- Intramural oesophageal haematoma following traumat...
- The 2-anilino-4-amino-5-aroylthiazole-type compoun...
- Exosomes Serve as Nano-particles to Suppress Tumor...
- C-C chemokine receptor type 1 mediates osteopontin...
- Implementation of “Clinical Sequencing” in Cancer ...
- Cancer Immunotherapy Targeted Glypican-3 or Neoant...
- Proposal for Reclassification of N Staging Systems...
- Regulatory mechanisms of HIF-1 activity: Two decad...
- The new metformin derivative HL156A prevents oral ...
- Nimotuzumab combined with concurrent chemoradiothe...
- Altered motor plasticity in an acute relapse of mu...
- Identifying and understanding the health and socia...
- Research protocol for the Picture Talk Project: a ...
- Effectiveness and cost-effectiveness of a guided i...
- Association of individual and neighbourhood socioe...
- Systematic evidence review of rates and burden of ...
- Pilot for the Australian Breast Device Registry (A...
- Applicability of evidence from previous systematic...
- Do biological disease-modifying antirheumatic drug...
- Implementation of a lung cancer multidisciplinary ...
- Long-term early development research in congenital...
- The renal parenchyma--evaluation of a novel ultras...
- Association of occasional smoking with total morta...
- Can we Save the rectum by watchful waiting or Tran...
- Exercise and adiposity in overweight and obese chi...
- Phenotype and genotype of muscle ryanodine recepto...
- Prognostic values of the integrated model incorpor...
- Formal models and quantitative measures of multise...
- Low-virulent Babesia venatorum infection masquerad...
- Editorial Board
- Potential demographic, clinical, and environment r...
- Choice of postoperative radiation for stage IIIA p...
- The effect of selective internal radiation therapy...
- High CEA levels in a case of resected colorectal c...
- Postoperative extracranial metastasis from gliobla...
- Synergistic inhibition of tumor growth by combinat...
- Galectin 3 expression in primary oral squamous cel...
- Clinicopathological factors influencing the outcom...
- c-MYC drives a subset of high-risk pediatric neuro...
- Patterns of bone tracer uptake on SPECT-CT in symp...
- Correction to: 18F-NaF PET/CT: EANM procedure guid...
- Validation of the mIBG skeletal SIOPEN scoring met...
- Correction to: Peptide receptor radionuclide thera...
- Quantitative 18 F-DOPA PET/CT in pheochromocytoma:...
- Repeatability of tumour hypoxia imaging using [ 18...
- Klaus Bohndorf, Mark Anderson, Mark Davies, Herwig...
- Invited editorial for the paper by Silvoniemi et a...
- All that glitters is not gold - new reconstruction...
- Added value of dedicated axillary hybrid 18F-FDG P...
- Delayed response after repeated 177 Lu-PSMA-617 ra...
- The role of interim FDG PET-CT after induction che...
- A score combining baseline neutrophilia and primar...
- Could 68 Ga-somatostatin analogues be an important...
- 68 Ga-PSMA 11 ligand PET imaging in patients with ...
- Texture analysis of high-resolution dedicated brea...
- Abstracts Presented at the Australian and New Zeal...
- Familial and Somatic BAP1 Mutations Inactivate ASX...
- Tumor treating fields (TTFields) delay DNA damage ...
- Editorial Board
- Development and Validation of an ICD-10-Based Disa...
- Pembrolizumab in Asia-Pacific patients with advanc...
- Bone marrow mesenchymal stem cells promote head an...
- Clinical Complications and Their Management
- Accurate prognostic awareness facilitates, whereas...
- Reply to “Prospective advances in fetal biomagneto...
- Oxaliplatin and neuropathy: A role for sodium chan...
- Observations on muscle activity in REM sleep behav...
- Prospective advances in fetal biomagnetometry – ch...
- Development, validation and utility of a simulatio...
- Sorafenib and fluvastatin synergistically alleviat...
- Failure of further validation for survival nomogra...
- Does seed migration increase the risk of second ma...
- Single Arm Phase II Trial of Elective Nodal Dose R...
- Real-time whole brain radiotherapy: A single insti...
- Kidney Function After a Hypertensive Disorder of P...
- Center Effects and Peritoneal Dialysis Peritonitis...
- Necrotizing soft tissue infection: clinical charac...
- Interaction of healthcare worker hands and portabl...
- Comparison of line probe assay to BACTEC MGIT 960 ...
- Diagnosing tuberculosis in hospitalized HIV-infect...
- The risk of nontuberculous mycobacterial infection...
- The Divalent Elements Changes in Early Stages of C...
- Whole Genome Sequencing of Candida glabrata for De...
- Improving prevention, monitoring and management of...
- Ankle ligament reconstruction after wide resection...
- Can testing clinical significance reduce false pos...
- Using incentives to recruit physicians into behavi...
- Lack of CT scanner in a rural emergency department...
- Nitrous oxide induced subacute combined degenerati...
- Lymphomas in IgG4-related disease: clinicopatholog...
- PET and MRI Guided Irradiation of a Glioblastoma R...
- Sequential Monte Carlo for inference of latent ARM...
- Anesthetic Management and Procedural Outcomes of P...
- Clinical Utility of Intraoperative Motor-Evoked Po...
- Exploring Beyond the Duration of Analgesia: Can Ad...
- Does Lactate Affect the Association of Early Hyper...
- A Simulation Study to Evaluate Improvements in Ane...
-
▼
Δεκ 28
(223)
- ► Σεπτεμβρίου (5105)
-
▼
Δεκεμβρίου
(5110)
-
►
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
- ► Φεβρουαρίου (793)
Αναζήτηση αυτού του ιστολογίου
Πέμπτη 28 Δεκεμβρίου 2017
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.