Optimal high dose rate brachytherapy fractionation scheme after keloid excision. A retrospective multicenter comparison of recurrence rates and complications

Keloid treatment with excision followed by brachytherapy is considered the most effective. However, the optimal fractionation scheme is unknown. Patient cohorts from three centers using 2x9 Gy, 3x6 Gy, or 2x6 Gy were analyzed. The scheme using 2x6 Gy had equally low recurrence and lower complication rates, showing a BED of 20 Gy is adequate in post-excisional HDR brachytherapy keloid treatment.

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