The precise cellular origin of cutaneous melanoma has been a topic of intense debate. Using a refined mouse model that faithfully recapitulates key histopathological features of early stages of human melanomagenesis, Köhler et al. report that melanoma can arise from mature, pigment-producing melanocytes located within the interfollicular epidermis.
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Πέμπτη 12 Οκτωβρίου 2017
Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes
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Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
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Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
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heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
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