Human Perinatal-Derived Biomaterials

Human perinatal tissues have been used for over a century as allogeneic biomaterials. Due to their advantageous properties including angiogenecity, anti-inflammation, anti-microbial, and immune privilege, these tissues are being utilized for novel applications across wide-ranging medical disciplines. Given continued clinical success, increased adoption of perinatal tissues as a disruptive technology platform has allowed for significant penetration into the multi-billion dollar biologics market. Here, we review current progress and future applications of perinatal biomaterials, as well as associated regulatory issues.

Biomaterials derived from human perinatal tissues have had widespread clinical success across multiple medical disciplines. This progress report provides an overview of their biological and mechanical properties as well as their current and future potential clinical applications. In addition, we review the current state of regulatory issues associated with perinatal biomaterial usage.

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