Identification of Plasmid-Mediated Quinolone Resistance in Salmonella Isolated from Swine Ceca and Retail Pork Chops in the United States [PublishAheadOfPrint]

Fluoroquinolones are important antimicrobial drugs used to treat human Salmonella infections, and resistance is rare in the United States for isolates from both human and animal sources. Recently, a number of Salmonella isolated from swine cecal contents and retail pork products from NARMS surveillance exhibited decreased susceptibility to ciprofloxacin. We identified two qnrB19 quinolone resistance plasmids as predominantly responsible for this phenomenon, and found them distributed among several Salmonella serotypes isolated throughout the United States.

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