Plasmids of diverse Inc groups disseminate the fosfomycin resistance gene fosA3 among Escherichia coli from pigs, chickens and dairy cows in Northeast China [PublishAheadOfPrint]

Thirty-nine fosfomycin-resistant E. coli isolates carrying fosA3 were obtained from pigs, chickens, dairy cows and staff in four Northeastern provinces of China during 06/2015-04/2016. The fosA3 was co-located with bla_CTX-M genes on conjugative plasmids of the incompatibility groups IncN (n=12), IncN-F33:A-:B- (n=2), IncF33:A-:B- (n=14), IncF14:A-:B- (n=2), and IncI1/ST136 (n=9). Four different genetic contexts of fosA3 were detected among the 39 E. coli isolates. Three potential epidemic plasmids circulated among E. coli strains from this region.

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