Publication date: Available online 27 July 2016
Source:Vaccine
Author(s): Azhar Choudhry, Julie Mathena, Jessica D. Albano, Margaret Yacovone, Limone Collins
Before the widespread adoption of vaccination, adenovirus type 4 and type 7 were long associated with respiratory illnesses among military recruits. When supplies were depleted and vaccination was suspended in 1999 for approximately a decade, respiratory illnesses due to adenovirus infections resurged. In March 2011, a new live, oral adenovirus vaccine was licensed by the US Food and Drug Administration and was first universally administered to military recruits in October 2011, leading to rapid, dramatic elimination of the disease within a few months. As part of licensure, a postmarketing study (Sentinel Surveillance Plan) was performed to detect potential safety signals within 42days after immunization of military recruits. This study retrospectively evaluated possible adverse events related to vaccination using data from the Armed Forces Health Surveillance Branch Defense Medical Surveillance System (DMSS) database. Among 100,000 recruits who received the adenovirus vaccine, no statistically significant greater risk of prespecified medical events was observed within 42days after vaccination when compared with a historical cohort of 100,000 unvaccinated recruits. In an initial statistical analysis of International Classification of Disease, 9th Revision, Clinical Modification codes, a statistically significant higher risk for 19 other (not prespecified) medical events occurring in 5 or more recruits was observed among vaccinated compared with unvaccinated groups. After case record data abstraction for attribution and validation, two events (psoriasis [21 vs 7 cases] and serum reactions [12 vs 4 cases]) occurred more frequently in the vaccinated cohort. A causal relation of these rare events with adenovirus vaccination could not be established given confounding factors in the DMSS, such as coadministration of other vaccines and incomplete or inaccurate medical information, for some recruits. Prospective surveillance assessing these uncommon, but potentially relevant, immune-related symptoms may be beneficial in defining potential causal association with adenovirus vaccination.
http://ift.tt/2awWyvT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
▼
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
-
▼
Ιουλίου
(489)
-
▼
Ιουλ 27
(49)
- Materials, Vol. 9, Pages 630: Fracture Properties ...
- Sensors, Vol. 16, Pages 1185: Monolithic Cylindric...
- Nutrients, Vol. 8, Pages 454: Validity and Reprodu...
- Nutrients, Vol. 8, Pages 458: Suppressive Effects ...
- Sensors, Vol. 16, Pages 1180: Object Detection App...
- Sensors, Vol. 16, Pages 1184: Three-Dimensional Ph...
- Sensors, Vol. 16, Pages 1182: Fast Object Motion E...
- IJERPH, Vol. 13, Pages 765: Endocrine Aspects of E...
- Sensors, Vol. 16, Pages 1181: Time-Varying Vocal F...
- Special Collection: Cell-Based Therapy for Bone Re...
- Study protocol for a randomised controlled trial t...
- Hundred top-cited articles focusing on acute kidne...
- Association of dental and periodontal disease with...
- Initial experience using a femtosecond laser catar...
- Sex differences in the risk profile of hypertensio...
- Special Collection: Cell-Based Therapy for Bone Re...
- Inside front cover
- Editorial Board
- Mercy Doc Appointed to National Academies' Quality...
- Mercy Gives $600,000 for Community Needs
- "Pokemon Go" is Latest Lesson in Digital Distractions
- Forming a Doctor-Patient Relationship
- Mercy Ranks in Top 5 Again and Again
- Sister’s Legacy Lives on through New Cancer Center
- More Hospitals Seek Software Support from Mercy
- Mercy Named Most Wired for 13th Time
- Beauty Queen’s Dream Still Alive
- Using Technology to Affect Influenza Vaccine Cover...
- Determination of Trace Water Content in Petroleum ...
- Fine needle aspiration cytology of cervical lymph ...
- CytoJournal Quiz Cases: Publishing open-access, Pu...
- Tuberculous lymphadenitis: Comparison of cytomorph...
- Contrasting female-male mortality ratios after rou...
- Changes in the anti-HBc profile of infants born to...
- Impact of PCV7/PCV13 introduction on invasive pneu...
- Complementary medicine and childhood immunisation:...
- Safety evaluation of adenovirus type 4 and type 7 ...
- To Your Health: NLM update: Salt linked to heart d...
- Molecular typing of human herpesvirus 8 among HIV ...
- The association between human papillomavirus (HPV)...
- Heterogeneous effects of oil shocks on exchange ra...
- Genotoxicity reduction in bagasse waste of sugar i...
- Cervical disc arthroplasty (CDA) versus anterior c...
- Establishing a framework to understand the regulat...
- To Your Health: NLM update: Exercise reduces cance...
- Endophenotype best practices
- Full title with Editorial board members
- Instructions to Authors
- IOP-details
-
▼
Ιουλ 27
(49)
- ► Φεβρουαρίου (793)
Αναζήτηση αυτού του ιστολογίου
Τετάρτη 27 Ιουλίου 2016
Safety evaluation of adenovirus type 4 and type 7 vaccine live, oral in military recruits
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.