SLIT ([i]sublingual immunotherapy[/i],) induces allergen-specific immune tolerance by sublingual administration of a gradually increasing dose of an allergen. The mechanism of SLIT is comparable to those during SCIT (subcutaneous immunotherapy), with the exception of local oral dendritic cells, pre-programmed to elicit tolerance. In the SLIT dose, to achieve the same efficacy as in SCIT, it should be 50–100 times higher with better safety profile. The highest quality evidence supporting the efficacy of SLIT lasting 1 – 3 years has been provided by the large scale double-blind, placebo-controlled (DBPC) trials for grass pollen extracts, both in children and adults with allergic rhinitis. Current indications for SLIT are allergic rhinitis (and conjunctivitis) in both children and adults sensitized to pollen allergens (trees, grass, [i]Parietaria[/i]), house dust mites ([i]Dermatophagoides pteronyssinus, Dermatophagoides farinae[/i]), cat fur, as well as mild to moderate controlled atopic asthma in children sensitized to house dust mites. There are positive findings for both asthma and new sensitization prevention. Severe adverse events, including anaphylaxis, are very rare, and no fatalities have been reported. Local adverse reactions develop in up to 70 – 80% of patients. Risk factors for SLIT adverse events have not been clearly identified. Risk factors of non-adherence to treatment might be dependent on the patient, disease treatment, physician-patient relationship, and variables in the health care system organization.
from #Medicine via ola Kala on Inoreader http://ift.tt/255Zoun
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
▼
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
-
▼
Μαρτίου
(699)
-
▼
Μαρ 17
(50)
- Previewing the 21st John H.P. Maley Lecture
- Previewing the 47th Mary McMillan Lecture
- Catalysts, Vol. 6, Pages 47: Homo-Polymerization o...
- Sinusitis, Vol. 1, Pages 49-54: Chronic Rhinosinus...
- Inhibition of Asthma in OVA Sensitized Mice Model ...
- The Effectiveness of Cupping Therapy on Relieving ...
- Attentional guidance by relative features: Behavio...
- Emotional responses to irony and emoticons in writ...
- Symmetry, Vol. 8, Pages 15: Low Dimensional Vessio...
- Energies, Vol. 9, Pages 214: Application of Breath...
- Symmetry, Vol. 8, Pages 14: Status of X(1835) and ...
- Viruses, Vol. 8, Pages 82: Roles of the Picornavir...
- Polymers, Vol. 8, Pages 90: Preparation of Uniform...
- Energies, Vol. 9, Pages 215: Evaluation of a Mixed...
- Remote Sensing, Vol. 8, Pages 255: Remote Sensing ...
- Remote Sensing, Vol. 8, Pages 258: An Automatic Bu...
- Evaluation of the anti-inflammatory action of curc...
- Exploration of the P3 region of PEXEL peptidomimet...
- Identification of Small-Molecule Compounds Targeti...
- Single-cell Mass Spectrometry with Multi-solvent E...
- Quantification of Tunicamycin-Induced Protein Expr...
- Long-term changes in dysnatremia incidence in the ...
- Ann Agric Environ Med 2016; 23(1):79-83 "Relations...
- Ann Agric Environ Med 2016; 23(1):106-110 "Cytotox...
- Ann Agric Environ Med 2016; 23(1):30-36 "Microarra...
- Ann Agric Environ Med 2016; 23(1):157-162 "Opinion...
- Ann Agric Environ Med 2016; 23(1):37-43 "Obesity a...
- Ann Agric Environ Med 2016; 23(1):125-128 "Clinica...
- Ann Agric Environ Med 2016; 23(1):44-53 "Sublingua...
- Ann Agric Environ Med 2016; 23(1):182-192 "Augment...
- Metals, Vol. 6, Pages 68: NURBS-Based Collocation ...
- Materials, Vol. 9, Pages 207: Fatigue Life Predict...
- IJMS, Vol. 17, Pages 395: Intronic Polymorphisms i...
- Materials, Vol. 9, Pages 205: Computational Study ...
- Molecules, Vol. 21, Pages 363: Comparison of the P...
- Lubricants, Vol. 4, Pages 8: Tribological Behaviou...
- Sensors, Vol. 16, Pages 384: A Differential Monoli...
- Cloning and Expression of the γ-Polyglutamic Acid ...
- Changes in pigment, spectral transmission and elem...
- Sponge distribution and the presence of photosymbi...
- Omega-3 fatty acids shown to exert a positive effe...
- IJMS, Vol. 17, Pages 392: Spatial Temporal Dynamic...
- Sensors, Vol. 16, Pages 388: Node Deployment Algor...
- Molecules, Vol. 21, Pages 367: Pharmacokinetics of...
- Pathogens, Vol. 5, Pages 32: Evasion of Neutrophil...
- Molecules, Vol. 21, Pages 368: Binding Mode and Se...
- Molecules, Vol. 21, Pages 365: Silver Nanoparticle...
- Energies, Vol. 9, Pages 212: Exergy Flows inside a...
- Molecules, Vol. 21, Pages 362: Searching for Multi...
- Entropy, Vol. 18, Pages 102: Development of a Refr...
-
▼
Μαρ 17
(50)
- ► Φεβρουαρίου (793)
Αναζήτηση αυτού του ιστολογίου
Πέμπτη 17 Μαρτίου 2016
Ann Agric Environ Med 2016; 23(1):44-53 "Sublingual immunotherapy (SLIT) – indications, mechanism, and efficacy Position paper prepared by the Section of Immunotherapy, Polish Society of Allergy"
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.