Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease
Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease: Cardiovascular diseases are chronic inflammatory diseases that affect a large segment of society. Coronary heart disease (CHD), the most common cardiovascular disease, progresses over several years and affects millions of people worldwide. Chronic infections may contribute to the systemic inflammation and enhance the risk for CHD. Periodontitis is one of the most common chronic infections that affects up to 50% of the adult population. Under inflammatory...περισσότερα »
„Okkulte“ metastasierte Melanome?
„Okkulte“ metastasierte Melanome?: Zusammenfassung FalldarstellungWir berichten über 2 Patienten, die uns im vergangenen Jahr mit der Diagnose metastasiertes okkultes Melanom vorgestellt wurden. Bei einer 60-jährigen Patientin fand sich im Bereich der Labia majora rechts ein livider derber Tumor. Die histologische Untersuchung ergab ein ulzeriertes noduläres Schleimhautmelanom mit Satellitenmetastasen. Bei einem 60-jährigen Patienten fanden sich im Bereich des Digitus (D) I der rechten Hand eine subunguale Hyperkeratose mit schwärzlichen Pigmenteinsprenkelungen und ein hautfarbene... περισσότερα »
Sleep disturbance as a proximal predictor of suicidal intent in recently hospitalized attempters
• A total of 127 hospitalised suicide attempters were interviewed within 2 weeks post-attempt.• The suicide attempters retrospectively assessed insomnia and mean sleep time for 2 weeks pre-attempt.• Insomnia, short sleep, and insomnia with short sleep predicted suicidal intent.• Insomnia and short sleep partially mediated various predictors' effect on intent.• Improving sleep in suicidal subjects may reduce the lethality of suicidal acts. from #SleepMedicine via ola Kala on Inoreader http://ift.tt/1lILITJ via IFTTT
Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease
Cardiovascular diseases are chronic inflammatory diseases that affect a large segment of society. Coronary heart disease (CHD), the most common cardiovascular disease, progresses over several years and affects millions of people worldwide. Chronic infections may contribute to the systemic inflammation and enhance the risk for CHD. Periodontitis is one of the most common chronic infections that affects up to 50% of the adult population. Under inflammatory conditions the activation of endogenous degradation pathways mediated by immune responses leads to the release of destructive ce... περισσότερα »
Genome-wide transcriptome induced by Porphyromonas gingivalis LPS supports the notion of host-derived periodontal destruction and its association with systemic diseases
Chronic periodontitis (CP) is a prevalent pathogen-associated inflammatory disorder characterized by the destruction of tooth-supporting tissues, and linked to several systemic diseases. Both the periodontopathogen *Porphyromonas gingivalis* (*Pg*), and the genetically determined host immune response, are hypothesized to play a crucial role in this association. To identify new target genes for CP and its associated systemic diseases, we investigated the transcriptome induced by *Pg* in human monocytes using a genome-wide approach. Monocytes were isolated from healthy male volunteer... περισσότερα »
Increased Proportion of Hematopoietic Stem and Progenitor Cell Population in Cord Blood of Neonates Born to Mothers with Gestational Diabetes Mellitus
Stem Cells and Development , Vol. 0, No. 0. from Cell via ola Kala on Inoreader http://ift.tt/1LywbKY via IFTTT
Association between age, gender and multimorbidity level and receiving home health care: a population-based Swedish study
Background: Home health care is an important part of primary health care. How delivery of home health care is organised is probably important for sustainability of the healthcare system as a whole. More than 50 % of individuals over 65 years old have multimorbidity, which increases with higher age, also influencing the needs of home health care. Our aim was to study the proportion of the population above 65 years receiving home health care according to age, gender and multimorbidity level. Methods: The study population comprised 32,130 people aged 65 or more, living in Blekinge Co... περισσότερα »
Effects of exercise on neuromuscular junction components across age: systematic review of animal experimental studies
Background: During almost one-third of our life, maturation of the nervous system promotes strength and muscle mass increase. However, as age advances, the nervous system begins to suffer a slow and continue reduction of its functions. Neuromuscular junction (NMJ) is one of the structures of which change due to aging process. Physical training leads to significant adjustments in NMJs of young and aged animals. Nevertheless, studies that aimed to investigate this effect have, in many cases, methodological variables that may have some influence on the result. Thus, this study aimed ...περισσότερα »
Surgical versus medical management of patients with acute ischemic mitral regurgitation: a systematic review
AimsAcute ischemic mitral regurgitation (MR) is seen in patients with myocardial infarction and is associated with increased morbidity and mortality. The optimal treatment strategy of this condition however, is not well established. The aim of this manuscript is to conduct a systematic review of the medical literature to assess the relative benefits and harms of mitral valve surgery with medical therapy versus medical management alone for patients with acute ischemic MR of at least moderate severity. Methods: We performed a literature search in MEDLINE, Embase.com, and Cochrane Ce... περισσότερα »
Ambient Mass Spectrometry Imaging Using Direct Liquid Extraction Techniques
[image: TOC Graphic] Analytical Chemistry DOI: 10.1021/acs.analchem.5b04188 [image: ancham?d=yIl2AUoC8zA] from #Medicine via ola Kala on Inoreader http://ift.tt/1XdUTwg via IFTTT
Protein Analysis by Ambient Ionization Mass Spectrometry Using Trypsin-Immobilized Organosiloxane Polymer Surfaces
[image: TOC Graphic] Analytical Chemistry DOI: 10.1021/acs.analchem.5b03669 [image: ancham?d=yIl2AUoC8zA] from #Medicine via ola Kala on Inoreader http://ift.tt/1XdURUY via IFTTT
Graphene Nanoribbon-Supported PtPd Concave Nanocubes for Electrochemical Detection of TNT with High Sensitivity and Selectivity
[image: TOC Graphic] Analytical Chemistry DOI: 10.1021/acs.analchem.5b03390 [image: ancham?d=yIl2AUoC8zA] from #Medicine via ola Kala on Inoreader http://ift.tt/1jiTmlY via IFTTT
Novel Fluorometric Method for the Determination of Production Rate and Steady-State Concentration of Photochemically Generated Superoxide Radical in Seawater Using 3′,6′-(Diphenylphosphinyl)fluorescein
[image: TOC Graphic] Analytical Chemistry DOI: 10.1021/acs.analchem.5b00917 [image: ancham?d=yIl2AUoC8zA] from #Medicine via ola Kala on Inoreader http://ift.tt/1XdUTfD via IFTTT
Acknowledgement to Referees
from #Medicine via ola Kala on Inoreader http://ift.tt/1jiTkKH via IFTTT
Brinzolamide–brimonidine for POAG and OHT
Sharma S, Trikha S, Perera SA, Aung T from #Medicine via ola Kala on Inoreader http://ift.tt/1jiTmlV via IFTTT
A Preliminary Genome-Wide Association Study of Acute Mountain Sickness Susceptibility in a Group of Nepalese Pilgrims Ascending to 4380 m
High Altitude Medicine & Biology , Vol. 0, No. 0. from #Medicine via ola Kala on Inoreader http://ift.tt/1jiTm5r via IFTTT
Detecting Arbitrary DNA Mutations Using Graphene Oxide and Ethidium Bromide
[image: TOC Graphic] Analytical Chemistry DOI: 10.1021/acs.analchem.5b03369 [image: ancham?d=yIl2AUoC8zA] from #Medicine via ola Kala on Inoreader http://ift.tt/1XdUQ3D via IFTTT
General Strategy for Enhancing Electrochemiluminescence of Semiconductor Nanocrystals by Hydrogen Peroxide and Potassium Persulfate as Dual Coreactants
[image: TOC Graphic] Analytical Chemistry DOI: 10.1021/acs.analchem.5b03890 [image: ancham?d=yIl2AUoC8zA] from #Medicine via ola Kala on Inoreader http://ift.tt/1TdyMQN via IFTTT
A Preliminary Genome-Wide Association Study of Acute Mountain Sickness Susceptibility in a Group of Nepalese Pilgrims Ascending to 4380 m
High Altitude Medicine & Biology , Vol. 0, No. 0. from #Medicine via ola Kala on Inoreader http://ift.tt/1jiTm5r via IFTTT
Chondrocalcinosis, Tumoral Calcinosis, - Everything You Need To Know - Dr. Nabil Ebraheim
Educational video describing the differences between Chondrocalcinosis, Tumoral Calcinosis, Synovial Chondromatosis, & Calcific Tendonitis Become a friend on facebook: http://ift.tt/1eMj35K Follow me on twitter: https://twitter.com/#!/DrEbraheim_UTMC Donate to the University of Toledo Foundation Department of Orthopaedic Surgery Endowed Chair Fund: http://ift.tt/1HCFAla from #Medicine via ola Kala on Inoreader https://www.youtube.com/watch?v=PUi8DjuNisc via IFTTT
SSVEP-based Experimental Procedure for Brain-Robot Interaction with Humanoid Robots
[image: 53558eq1.jpg] The overall goal of this method is to establish an SSVEP-based experimental procedure by integrating multiple software programs to enable the study of brain-robot interaction with humanoid robots, which is prospective in assisting the sick and elderly as well as performing unsanitary or dangerous jobs. from #Medicine via ola Kala on Inoreader http://ift.tt/1XdUQQZ via IFTTT
Increased Proportion of Hematopoietic Stem and Progenitor Cell Population in Cord Blood of Neonates Born to Mothers with Gestational Diabetes Mellitus
Stem Cells and Development , Vol. 0, No. 0. from Cell via ola Kala on Inoreader http://ift.tt/1LywbKY via IFTTT
Kidney transplantation in infantile myofibromatosis and fibromuscular dysplasia: a case report
[image: s13256-015-0756-8-1.gif] IntroductionWe report what we believe to be the first case of a child affected by two rare vascular diseases complicated by kidney failure and successfully treated by kidney transplantation.Case presentationA 3-year-old Caucasian girl with fibromuscular dysplasia and infantile myofibromatosis presented with arterial hypertension and renal failure. She received a deceased donor kidney transplantation distal to an iliac graft. The technical peculiarities of this transplantation are described, as well as her favorable long-term outcome. Conclusion: Kid... περισσότερα »
Postpartum vertebral artery dissection
We report a case of a right vertebral artery dissection in a 35-year-old woman, 3 weeks post partum, with manifestations of vertebrobasilar disease. She was 3 weeks out from the uneventful delivery of her fourth child, with presentation of acute neurological symptoms, predominantly intractable vertigo. Vertigo can have many non-specific generalised symptoms and clinical findings. Postpartum women have a lengthy list of possible aetiologies of vertigo not limited to our initially suspected preeclampsia, dural venous thrombosis and vertebral dissection. from Cases via ola Kala on I... περισσότερα »
Salmonella newport causing osteomyelitis in a patient with diabetes
*Salmonella* is a foodborne pathogen that commonly causes intestinal symptoms. Bacteraemia and extraintestinal infections have been documented within the literature, and are more frequently associated with immunodeficiency and general debilitation. We discuss the case of a previously well 36-year-old man who presented with a septic knee and new-onset diabetes. Imaging confirmed osteomyelitis and a Brodie's abscess, with blood and tissue cultures revealing the isolate *Salmonella enterica newport*. He denied any previous gastrointestinal symptoms, recent travel, change in usual die...περισσότερα »
Filarial hydropneumothorax: a strange journey
Filarial infection can have varied manifestations, but hydropneumothorax at presentation has not yet been reported. A 28-year-old man presented to our hospital with heaviness of the left chest for the past 10 days, which was preceded by a sudden, short stabbing pain in the left chest after straining. Chest X-ray revealed left-sided hydropneumothorax. A peripheral blood picture revealed significant eosinophilia. A pleural fluid report also showed eosinophilia and a few motile microfilaria of *Wuchereria bancrofti*. Microfilaria was also documented in peripheral blood. There was no ... περισσότερα »
Inferior mesenteric vein pylephlebitis due to sigmoid diverticulitis
Description A 55-year-old man was admitted to the emergency department, with high fever. Physical examination revealed a soft abdomen without any signs of peritoneal irritation and bowel sounds were normal. Laboratory tests revealed elevation of white cell count (11.5x103/mm3) and C reactive protein. Contrast-enhanced CT showed sigmoid colon diverticulosis and increasing stranding of fat tissue adjacent to the sigmoid colon, in keeping with diverticulitis (figure 1). In addition, complete thrombosis of the inferior mesenteric vein (IMV) with intraluminal filling defect, periveno... περισσότερα »
Extremely high HIV-1 viral load in a patient with undiagnosed clinical indicator disease for HIV infection
We report a case of a new diagnosis of HIV with an extremely high viral load presenting with HIV encephalopathy, in a 54-year-old woman who had been treated with 2 years of extended high-dose immunosuppressant therapy for a recalcitrant pruritic rash before diagnosis. from Cases via ola Kala on Inoreader http://ift.tt/1Oet8xM via IFTTT
Elderly care between global and local services: the use of somatic care practices
Israel's population is ageing alongside the worldwide ageing population. As the population ages and the number of older people who are 'ageing in place' increases, the system of elderly care will face new opportunities and challenges in responding to non-institutional services for elderly care. There is an increasing demand for foreign caregivers despite differences in language and cultural background. This case report describes the global care services provided in Israel by caregivers from the Philippines to emphasis the cultural and social components of elderly care. The followi... περισσότερα »
An example of prompt and appropriate multidisciplinary management leading to an exceptionally good outcome: a case complicated by amniotic fluid embolism
Amniotic fluid embolism (AFE) is a rare and serious phenomenon; we describe a rare case of AFE occurring after a second trimester surgical termination in a private clinic, which, with prompt transfer and appropriate multidisciplinary management, had an exceptionally good outcome. The patient developed hypotension, respiratory arrest and disseminated intravascular coagulopathy following the procedure but with aggressive management she made a full recovery without any neurological or long-term sequelae. from Cases via ola Kala on Inoreader http://ift.tt/1MPhXHw via IFTTT
A 43-year-old woman presenting with subacute, bilateral, sequential facial nerve palsies, then developing pseudotumour cerebri
A patient presented elsewhere with what appeared to be a simple, unilateral, chronic suppurative otitis media and then developed an ipsilateral facial palsy. She soon developed the same problem on the other side. At the time, a brain MRI had been ordered but the clinician did not review it with a radiologist. The surgical specimens were not sent for histopathology. When transferred to our institution 3 months later, the patient had severe bilateral papilloedema due to intracranial hypertension due to missed cerebral venous sinus thrombosis. Further surgery revealed that the pathol... περισσότερα »
Septic arthritis and subsequent fatal septic shock caused by Vibrio vulnificus infection
*Vibrio vulnificus* is a rare but potential fatal bacterium that can cause severe infections. Wound infections, primary sepsis and gastroenteritis are the most common clinical features. Septic arthritis caused by *V. vulnificus* is an atypical presentation that has been reported in only two case reports; however, it has not been previously noted in Denmark. The authors report a case of septic arthritis caused by *V. vulnificus* in an immunocompromised patient. The disease progressed to severe sepsis and subsequent death within 10 h of admission. from Cases via ola Kala on Inoread...περισσότερα »
Ulnar artery aneurysm and hypothenar hammer syndrome
Description A right-hand dominant patient presented with pain and a tender mass in the hypothenar eminence, and with paraesthesia of the fourth and fifth fingers. The patient was referred for MRI of the hand, which showed thrombosed ulnar artery aneurysm and an irregularity of the superficial ulnar artery, suggesting a diagnosis of hypothenar hammer syndrome (HHS) (figures 1 and 2). Figure 1 Axial short tau inversion recovery image at the level of the hook of hamate (larger arrow) showing ulnar artery aneurysm (smaller arrow). Figure 2 Sagittal short tau inversion recovery ima... περισσότερα »
Filarial hydropneumothorax: a strange journey
Filarial infection can have varied manifestations, but hydropneumothorax at presentation has not yet been reported. A 28-year-old man presented to our hospital with heaviness of the left chest for the past 10 days, which was preceded by a sudden, short stabbing pain in the left chest after straining. Chest X-ray revealed left-sided hydropneumothorax. A peripheral blood picture revealed significant eosinophilia. A pleural fluid report also showed eosinophilia and a few motile microfilaria of *Wuchereria bancrofti*. Microfilaria was also documented in peripheral blood. There was no ... περισσότερα »
Inferior mesenteric vein pylephlebitis due to sigmoid diverticulitis
Description A 55-year-old man was admitted to the emergency department, with high fever. Physical examination revealed a soft abdomen without any signs of peritoneal irritation and bowel sounds were normal. Laboratory tests revealed elevation of white cell count (11.5x103/mm3) and C reactive protein. Contrast-enhanced CT showed sigmoid colon diverticulosis and increasing stranding of fat tissue adjacent to the sigmoid colon, in keeping with diverticulitis (figure 1). In addition, complete thrombosis of the inferior mesenteric vein (IMV) with intraluminal filling defect, perivenou... περισσότερα »
Extremely high HIV-1 viral load in a patient with undiagnosed clinical indicator disease for HIV infection
We report a case of a new diagnosis of HIV with an extremely high viral load presenting with HIV encephalopathy, in a 54-year-old woman who had been treated with 2 years of extended high-dose immunosuppressant therapy for a recalcitrant pruritic rash before diagnosis. from Cases via ola Kala on Inoreader http://ift.tt/1Oet8xM via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via paythelady61 on Inoreader http://ift.tt/1kSnsyi via IFTTT
Elderly care between global and local services: the use of somatic care practices
Israel's population is ageing alongside the worldwide ageing population. As the population ages and the number of older people who are 'ageing in place' increases, the system of elderly care will face new opportunities and challenges in responding to non-institutional services for elderly care. There is an increasing demand for foreign caregivers despite differences in language and cultural background. This case report describes the global care services provided in Israel by caregivers from the Philippines to emphasis the cultural and social components of elderly care. The followi... περισσότερα »
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