Radiolabeled peptides (radiopeptides) are very powerful tools for diagnostic imaging and radionuclide therapy of various diseases. Since the introduction of the first radiopeptide into the clinical setting to diagnose neuroendocrine tumors (NETs) about 25 years ago, many advances have been made in the field. This short review aims to highlight novel strategies to improve the application of radiopeptides for imaging and therapy.
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