The Purkinje network is a specialized conduction system within the heart that ensures the proper activation of the ventricles to produce effective contraction. Its role during ventricular arrhythmias is less clear, but some experimental studies have suggested that the Purkinje network may significantly affect the genesis and maintenance of ventricular arrhythmias. Despite its importance, few structural models of the Purkinje network have been developed, primarily because current physical limitations prevent examination of the intact Purkinje network. In previous modeling efforts Purkinje-like structures have been developed through either automated or hand-drawn procedures, but these networks have been created according to general principles rather than based on real networks. To allow for greater realism in Purkinje structural models, we present a method for creating three-dimensional Purkinje networks based directly on imaging data. Our approach uses Purkinje network structures extracted from photographs of dissected ventricles and projects these flat networks onto realistic endocardial surfaces. Using this method, we create models for the combined ventricle-Purkinje system that can fully activate the ventricles through a stimulus delivered to the Purkinje network and can produce simulated activation sequences that match experimental observations. The combined models have the potential to help elucidate Purkinje network contributions during ventricular arrhythmias.
from #Medicine via ola Kala on Inoreader http://ift.tt/1i5AfLv
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
►
2018
(66471)
- ► Δεκεμβρίου (5242)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
►
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
- ► Φεβρουαρίου (793)
-
▼
2015
(2119)
- ► Δεκεμβρίου (940)
-
▼
Οκτωβρίου
(414)
-
▼
Οκτ 25
(39)
- Instrumentation of Near-term Fetal Sheep for Multi...
- Catecholic amides as potential selective phosphodi...
- Helical peptide–polyamine and –polyether conjugate...
- Bivalent ligands incorporating curcumin and diosge...
- Synthesis and biological evaluation of di-aryl ure...
- Does Computer-Assisted Femur First THR Improve Mus...
- Hyaluronan’s Role in Fibrosis: A Pathogenic Factor...
- Application of Mathematical Modeling for Simulatio...
- Simulation of Ectopic Pacemakers in the Heart: Mul...
- Dental Implants Fatigue as a Possible Failure of I...
- Increased Expression of Serglycin in Specific Carc...
- Vapotage chez les étudiants à l’université et rela...
- Functional and Phenotypic Plasticity of CD4+ T Cel...
- Recent Advances on Pathophysiology, Diagnostic and...
- In Vivo Targeted Magnetic Resonance Imaging of End...
- Revisiting the Posttherapeutic Cure Criterion in C...
- Species Composition and Diversity of Malaria Vecto...
- Organotypic Cultures of Intervertebral Disc Cells:...
- Effects of Fourteen-Day Bed Rest on Trunk Stabiliz...
- The Impact of a Vestibular-Stimulating Exercise Re...
- Effects of Surface Modification and Bulk Geometry ...
- Vitamin A Impairs the Reprogramming of Tregs into ...
- High LIN28A Expressing Ovarian Cancer Cells Secret...
- Simulating Cardiac Electrophysiology Using Unstruc...
- An Overview of the Mechanical Integrity of Dental ...
- T Helper Subsets, Peripheral Plasticity, and the A...
- Effects of Exercise on Spinal Deformities and Qual...
- Cognitive Interventions in Older Persons: Do They ...
- Characterization of Electrograms from Multipolar D...
- A Comprehensive Review on Cyclodextrin-Based Carri...
- Hexosamine-Induced TGF-β Signaling and Osteogenic ...
- Tinnitus and Headache
- The Effect of Risk Factors on the Levels of Chemic...
- Image-Based Structural Modeling of the Cardiac Pur...
- The Association between Cerebral White Matter Lesi...
- Epidemiology of rubella and congenital rubella syn...
- A cytomegalovirus DNA vaccine induces antibodies t...
- Analyse coût-efficacité de l’introduction du vacci...
- Neptunism and Transformism: Robert Jameson and oth...
-
▼
Οκτ 25
(39)
Αναζήτηση αυτού του ιστολογίου
Κυριακή 25 Οκτωβρίου 2015
Image-Based Structural Modeling of the Cardiac Purkinje Network
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
Alimentary Pharmacology &Therapeutics, EarlyView. https://ift.tt/2qECBIJ
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.