hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids

Xiang and colleagues report a method for generating human thalamus-like brain organoids (hThOs) that recapitulate the development of human thalamus. By fusing hThOs and cortical-like brain organoids (hCOs), they establish a 3D system in a dish to create the reciprocal projections between thalamus and cortex.

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