Endoscopic ultrasound‐guided tissue acquisition: Can fork and crown cut the tissue?

Abstract

Tissue acquisition under endoscopic ultrasound‐guided fine needle aspiration (EUS‐FNA) is important in obtaining a pathological diagnosis in certain malignant and benign diseases. These include well‐differentiated adenocarcinomas, autoimmune pancreatitis, and sarcoidosis. Tissue specimens also allow for additional immunohistological evaluation, which is essential in the diagnosis of diseases such as lymphoma, neuroendocrine neoplasms, and gastrointestinal stromal tumors. More recently, tissue specimens have been of great importance in decision‐making pertaining to the administration of specific medicines, such as molecular target agents, as well as the use of molecular biological diagnostic approaches.

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