Dual-Phase 18F-FP-CIT PET in Corticobasal Syndrome

Corticobasal syndrome is the most common phenotype of corticobasal degeneration (CBD). 18F-FP-CIT PET and MRI are not helpful in distinguishing CBD from idiopathic Parkinson disease. Dual-phase 18F-FP-CIT PET is a recently developed imaging that shows regional cerebral perfusion in the early phase and dopamine transporter density in the late phase. We investigated the usefulness of dual-phase 18F-FP-CIT PET imaging in 3 patients with corticobasal syndrome. This image highlights that the early phases of 18F-FP-CIT PET may reflect regional cerebral perfusion with a pattern very similar to that of regional glucose metabolism in CBD.

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