Reduced delta-band modulation underlies the loss of P300 responses in disorders of consciousness

A significant challenge in the scientific study of disorders of consciousness (DoC) is the identification of brain activity that characterizes a patient's remnant cognitive or perceptual functions. In the vegetative state (VS), also defined as unresponsive wakefulness syndrome (Laureys et al., 2010), this identification is especially critical. VS patients are characterized by a persistent inability to express behaviors that reflect will or purpose, either spontaneously or in response to sensory stimuli.

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