Internal mammary node irradiation (IMNI) improves survival outcome for patients with clinical stage II-III breast cancer after preoperative systemic therapy

This study is designed to evaluate the effect of internal mammary node irradiation (IMNI) in breast cancer patients after preoperative systemic therapy and surgery. We reviewed patients with clinical stage II-III breast cancer who underwent NAC and postoperative radiotherapy with or without IMNI. Patients in IMNI group showed improved survival outcomes, especially those with residual disease of the primary lesion and pathologically positive nodes.

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