High-Risk Clonal Hematopoiesis as the Origin of AITL and NPM1-Mutated AML

To the Editor: Clonal hematopoiesis of indeterminate potential (CHIP) is associated with an increased risk of hematologic neoplasms. CHIP is most common in older patients, who usually carry a single somatic mutation (which provides a fitness advantage) in a minority of hematopoietic cells. Here, we…

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