Depression Characterization and Race among Stroke Survivors Receiving Inpatient Rehabilitation

Race and ethnicity play a significant role in post-stroke outcomes. This brief report describes the presence of depression among stroke survivors who received inpatient rehabilitation and whether depression differs by race. Data from eRehabData® and electronic medical records were analyzed for patients who received rehabilitation after an acute ischemic or hemorrhagic stroke. Of 1501 stroke patients, 61.3% were White, 33.9% were African American (AA) and 4.8% were of other race/ethnic backgrounds. By retrospective clinical review, depression was documented for 29.7% of stroke patients. Pre-morbid versus new onset of post-stroke depression was documented for 13.4% and 21.6% of Whites, 7.5% and 11.5% of AA, and 0% and 16.7% of patients of other race/ethnic groups. Compared with Whites, AA and people of other races had a lower odds of post-stroke depression (AA adjusted odds ratio [OR]=0.52, 95% confidence interval [CI]=0.41-0.68; other races OR=0.37, 95% CI=0.19-0.71), after adjusting for all other significant risk factors identified in the bivariate analysis (sex, hyperlipidemia, cognitive deficit, neglect). Depression was documented for one in three stroke survivors who received inpatient rehabilitation, and highest among Whites especially for pre-stroke depression. Addressing depression in rehabilitation care needs to consider individual patient characteristics and pre-stroke health status. Corresponding author: Janet Prvu Bettger, ScD, FAHA; DUMC 2919, 40 Medicine Circle, Durham, NC, 27710; Office: 919-613-0379; Email: janet.bettger@duke.edu Funding Disclosure: This work was supported in part by NIH NR25GM102739, NIH/NINR P30NR014139, and institutional grants from Duke University School of Nursing and Cannon Research Center Carolinas Medical Center Author Disclosures or Conflicts of Interest: Nothing disclose from any author Previous Dissemination: Preliminary findings for this study were presented by Gabrielle M Harris at the International Stroke Conference on February 12, 2015 in Nashville, Tennessee. The presentation was entitled: "Depression differs by race among stroke survivors receiving inpatient rehabilitation" and the abstract was published as Harris GM, Thomas JG, Nguyen V, Hirsch MA, Guerrier T, Hamm D, Pereira C, Bettger JP. Depression differs by race among stroke survivors receiving inpatient rehabilitation. Stroke 2015;46(Suppl 1):ATP129-ATP129. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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