Endoscopic Mucosal Resection Versus Endoscopic Submucosal Dissection for Barrett’s Esophagus and Colorectal Neoplasia

Endoscopic resection has become the first-line therapy for the management of superficial neoplasia throughout the gastrointestinal tract. Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are established yet distinct techniques for the treatment of superficial gastrointestinal neoplasia. EMR is simpler and faster but is limited by its ability to resect large lesions en-bloc. Limitations of piecemeal EMR of large lesions include a high rate of recurrence and a less than ideal tissue specimen for accurate histologic evaluation.

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