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Τετάρτη 1 Αυγούστου 2018

Optimal allocation of bacterial protein resource under nonlethal protein maturation stress

Under different environmental stresses, bacteria optimize the allocation of cellular resources through a variety of mechanisms. Recently, researchers have used phenomenological models to quantitatively characterize the allocation of bacterial protein resources under metabolic and translational limitations. Some stresses interfere with protein maturation, thereby enhancing the expression of chaperones and proteases. However, the reallocation of protein resource caused by such environmental stresses has not been modeled quantitatively.

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