EUS-Guided Fine Needle Tissue Acquisition for Pancreatic Solid Lesions: Are We at the End of Fine Needle Aspiration?

We read with interest the randomized controlled study by Bang et al,1 which compared endoscopic ultrasound (EUS) fine-needle aspiration (FNA) performed with a 22G needle with or without suction or with a 25G needle with or without suction in 352 patients with pancreatic solid lesions (PSLs). The primary outcome was diagnostic accuracy of cell-block, whereas secondary outcomes were the comparison of operating characteristics of rapid on-site cytopathology (ROSE) and EUS-FNA, the number of passes to establish onsite diagnostic adequacy, the specimen bloodiness, adverse events, and technical failure.

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