The ulnar ratio as a sensitive and specific marker of acute inflammatory demyelinating polyneuropathy

Acute inflammatory demyelinating polyneuropathy (AIDP) is an acute demyelinating neuropathy classically defined as ascending paralysis associated with areflexia (Guillain et al., 1916). Sensory symptoms are common and occur early in the course of the disease, often before the onset of significant motor weakness. Diagnosis is based on a typical clinical picture, characteristic cerebrospinal fluid findings, and evidence of widespread demyelination on nerve conduction studies (NCS). The commonly used electrodiagnostic (EDX) criteria rely exclusively on the motor NCS findings (Ho et al., 1995, Hadden et al., 1998, Van Den Bergh et al., 2004) despite the widely recognized value of sensory abnormalities in the diagnosis of GBS (Albers et al., 1985, Gordon et al., 2001, Kuwabara et al., 2004, Al-Shekhlee et al., 2005, Al‐Shekhlee et al., 2007).

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