Role of daily plan adaptation in MR-guided stereotactic ablative radiotherapy for adrenal metastases

Stereotactic ablative radiotherapy (SABR) delivered during shallow inspiration breath-hold under MR-guidance, was implemented for adrenal gland metastases. We studied inter-fractional changes in GTV and OARs, and also the role of online plan re-optimization in ensuring both adequate target coverage and OAR sparing. Online plan adaptation led to improved target coverage in 63% of treatment fractions, and significantly reduced OAR doses. Our results indicate that online plan adaptation is beneficial in adrenal SABR.

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