The Use of Functional MRI in Cervical Cancer Patients with Incomplete Response on PET/CT Following Image-Based High-Dose Rate Brachytherapy

While the outcomes of definitive chemoradiation therapy for cervical cancer continue to improve, identifying patients at risk for early post-treatment failure remains a challenge. We have investigated the prognostic value of post treatment PET/CT metabolic response and functional MRI in an effort to hasten the diagnosis of persistent disease following definitive treatment. This report describes our findings in a series of 244 patients with clinical stage IB1-IVA cervical cancer treated with image-based HDR brachytherapy.

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