qSOFA, Cue Confusion

In this issue, a systematic review by Fernando and colleagues compares the prognostic accuracy of the quick Sequential (Sepsis-related) Organ Failure Assessment (qSOFA) and the systemic inflammatory response syndrome (SIRS) criteria for identification of patients with sepsis. The editorialists discuss the confusion surrounding sepsis scores and note that neither qSOFA nor the SIRS criteria are diagnostic for infection or sepsis, although they do offer information on the host's inflammatory reaction to an insult and the degree of physiologic perturbation.

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