Magnetic drug targeting simulations in blood flows with fluid-structure interaction

Summary

We present fluid-structure interaction (FSI) simulations of magnetic drug targeting (MDT) in blood flows. In this procedure, a drug is attached to ferromagnetic particles in order to externally direct it to a specific target after it is injected inside the body. The goal is to minimize the healthy tissue affected by the treatment and to maximize the number of particles that reach the target location. MDT has been studied both experimentally and theoretically by several authors. In recent years, computational fluid dynamics (CFD) simulations of MDT in blood flows have been carried out to obtain further insight on the combination of parameters that provide the best capture efficiency. However, to this day, no computational study addressed MDT in an FSI setting. With this paper, we aim to fill this gap and investigate the impact of the solid deformation on the capture efficiency. This article is protected by copyright. All rights reserved.

http://ift.tt/2zmtJZM