Diminished EEG Habituation to Novel Events Effectively Classifies Parkinson’s Patients

Some of the most debilitating aspects of Parkinson's disease include cognitive and mood disturbances. While it is widely appreciated that cell death in Parkinson's disease somehow contributes to deficits in higher cognitive functioning, the mechanisms underlying these deficits remain unclear. Executive dysfunction is common in Parkinson's disease (Dirnberger and Jahanshahi, 2013; Eberling et al., 2014; Robbins and Cools, 2014), yet one sub-process stands out as being specifically compromised: diminished orienting responses to novel stimuli (Kingstone et al., 2002; Poliakoff et al., 2003; Yamaguchi and Kobayashi, 1998; Zhou et al., 2012).

http://ift.tt/2Cf1mz4