Clinical Variables for Prediction of the Therapeutic Effects of Bevacizumab Monotherapy in Nasopharyngeal Carcinoma Patients with Radiation-induced Brain Necrosis

We underwent this retrospective study to identify the predictive and prognostic factors for brain edema decrease or recurrence after bevacizumab monotherapy in patients who developed radiation-induced brain necrosis (RN) after nasopharyngeal carcinoma. We have developed prediction models for the therapeutic effect of bevacizumab in RN patients by using random forests. Bevacizumab might be more effective in patients with lower maximum radiation dose of the temporal lobe.

http://ift.tt/2hGeLHp