Multiplex proximity ligation assay to identify potential prognostic biomarkers for improved survival in locally advanced pancreatic cancer patients treated with stereotactic body radiation therapy

In locally advanced pancreatic cancer (LAPC), the role of stereotactic body radiotherapy (SBRT) is evolving. Non-invasive seromarkers are needed to define prognosis. A proximity ligation assay (PLA) can evaluate expression levels of proteins that may correlate with outcomes. Herein, seromarker levels were explored for associations with outcomes in LAPC patients who received chemotherapy and SBRT.

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