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Τετάρτη 9 Αυγούστου 2017

Parkinsonian rest tremor can be detected accurately based on neuronal oscillations recorded from the subthalamic nucleus

Deep brain stimulation (DBS) is a widely used treatment for patients with advanced Parkinson's disease (Perlmutter and Mink 2006). While its efficacy is well established, its efficiency can potentially be optimized. Conventional DBS is applied continuously although motor symptoms are usually fluctuating. Moreover, the benefit of DBS is often compromised by side-effects, which can usually be alleviated by reducing stimulation power, i.e. the energy applied per unit of time. Suggested approaches to reduce power include electric field steering (Contarino et al.

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