Electroencephalogram dynamics in children during different levels of anaesthetic depth

Loss of consciousness induced by general anaesthetic agents has been proposed to be related to disruptions of connectivity between neuronal networks of the thalamus and the cerebral cortex (Alkire et al., 2000). Accordingly, the electroencephalogram (EEG), as a tool to measure synchronicity of network connectivity, has gained a position as the de-facto standard to monitor the depth of anaesthesia. However, EEG signatures used to identify different levels of anaesthesia are not well characterized in children, and still need to be properly described before implementation in clinical practice.

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