Newer GFR Estimating Equations Require Validation in Different Populations

In a recent research letter, Levey et al1 concluded that the new creatinine-based equations for estimating glomerular filtration rate (GFR), namely the Lund Malmö revised (LMR)2 and full-age spectrum (FAS),3,4 were not more accurate compared to the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation in adults. As authors of the FAS equations,3,4 we question this conclusion, which we believe was based on inappropriate comparisons. First, part of the comparison is based on the development database of the CKD-EPI equation.

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