Cancer Therapy: Injectable Supramolecular Hydrogels as Delivery Agents of Bcl-2 Conversion Gene for the Effective Shrinkage of Therapeutic Resistance Tumors (Adv. Healthcare Mater. 11/2017)

In article number 1700159, Zibiao Li, Xian Jun Loh, Yun-Long Wu, and co-workers design injectable MPEG-PCL-PEI/α-CD based supramolecular hydrogels that possess good sustained release ability of Bcl-2 conversion genes in form of polyplex, to effectively inhibit in vivo tumor growth. This long term "enemy to friend" strategy will benefit various applications, including on-demand gene delivery and personalized medicine.

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