Itsuki Ajioka and co-workers report a laminin-sponge (purple) with affinity-immobilized VEGF (yellow), which is an angiogenic growth factor. Neovascularization from existing blood vessels (red) in ischemic brain can potentially prevent the excess death of neurons (cyan) and improve functional recovery. The angiogenic activity of this sponge in vivo in a mouse stroke model is demonstrated in article number 1700183.
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